manufacturing jobs

Near blackburn, north west
382Jobs Found

382 jobs found for manufacturing jobs Near blackburn, north west

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Manufacturing Manager - Cell Therapy

Instil Bio

Greater Manchester, NW
22 days ago
Greater Manchester, NW
22 days ago

About Instil Bio

Instil Bio is a cell therapy company developing tumor infiltrating lymphocytes (TIL) for the treatment of solid tumor cancers. TIL are a patient’s own T cells harvested from the patient’s tumor, which are then expanded and reinfused into the patient to target and kill cancer cells. Instil is advancing its proprietary TIL manufacturing expertise, technology, and data into clinical trials, including a planned registrational study with its lead candidate and a first-in-human study of its next-generation engineered TIL. The company is led by world-class cell therapy experts and backed by premier global institutional investors.

Instil Bio UK is Instil’s rapidly-growing, Manchester UK-based subsidiary. Our Manchester subsidiary has significant R&D, process development, and clinical manufacturing capabilities, with approximately 35 staff expanding to > 100 staff. Instil Bio UK has been generating cell therapy products for patient use since 2011, including TIL products and external partner genetically engineered T cell products.

Manufacturing Manager – Cell Therapy

Instil Bio UK is now recruiting a Manufacturing Manager, responsible for supporting the Director of Manufacturing (UK) in building, training, managing and mentoring manufacturing staff within the Manufacturing function at Instil Bio (UK)’s clinical manufacturing facilities in Manchester, UK. You will be responsible for leading, developing and managing staff to manufacture batches to meet clinical demand, achieve improvements in planned aseptic manufacturing production, pharmaceutical awareness, cGMP, capacity utilisation, quality, cost and supply plans and activities in compliance with company, regulatory, pharmaceutical standards.

As the Manufacturing Manager you will be required to: 

•    Support the Dir. Of Manufacturing in strategic planning and leadership to meet site and global objectives. 

•    To recruit, train, develop and coach technical team members such that increased focus is put on pharmaceutical awareness and operating standards as well as job skills and knowledge of an advanced therapy medicinal product (ATMP)

•    Ensure manufacturing operations adhere to regulatory requirements (US, UK, and EU) 

•    Work with QC and QA to ensure on-time product release per specification 

•    Work with supply chain to plan production schedules, receive material and execute on-time product manufacturing 

•    Through implementation of Continuous Improvement philosophy, manage and improve pharmaceutical standards, awareness & compliance within the technical team (measures: CAPA close out, NCR close out, clean room standards, engineering standards); 

•    Implement operational excellence principles to ensure accelerating manufacturing cadence meets clinical targets 

•    Setting, communicating, tracking, and reporting KPI’s at a personal and departmental level 

•    Champion a continuous improvement culture; work cross-functionally with Manufacturing Sciences and Technology (MS&T) and Quality to improve manufacturing operations in a compliant manner 

•    Work cross-functionally on new product introduction and process changes (transfers, improvements, validation) 

•    Ensure processes are followed for change controls, deviations/investigations, CAPAs, process transfers, validations, risk analysis, and mitigations

The role is not required to be on a shift pattern but will require establishing multiple teams and shifts to deliver product through clinical trial according to targets. Flexibility may be required to take calls or do some work from home outside normal business hours.

Relevant Education Skills and Experience

This role will involve hiring and building teams along with team management. It will involve developing and leading other manufacturing and manufacturing support staff. To be successful it is anticipated you will have gained the following skills, traits, and experience:

•    Team management and people development. Ability to successful manage manufacturing operations through good planning and resourcing. Eye for detail to ensure right first-time operational excellence.

•    At least 5 years of experience managing operational teams Managing at least 12 staff. Experience of implementing strategic decisions through organised teams. Experience representing manufacturing on large multi-disciplinary project teams 10+ years relevant GMP aseptic cell culture manufacturing experience (e.g. cell therapy, gene therapy, biologics, vaccine)

•    BS degree in life sciences, engineering or related field, advanced degree, e.g. MS, MBA, and/or PhD preferred Quality Systems used in GMP environments Knowledge of GMPs and compliance within the biopharmaceutical industry

•    A target driven team builder who enjoys working in a fast-paced environment

•    Detailed planning and resource management Very good communication and interpersonal motivation skills Ability to accommodate flexible working hours depending on work nee

The following experience may be considered an advantage but is by no means essential to a successful application:

•    Guidance and compliance with MHRA, HTA, European Directives or FDA guidance for Cell Therapies

•    Experience in cell therapies/ATMPs 

•    Experience with managing shift working

Remuneration & Benefits

The salary for the Manufacturing Manager will be competitive within the Biotechnology and wider Scientific sector with actual salary offered reflecting relevant qualifications and experience as well as performance at interview. In any event we anticipate a salary in the £45,000 to £55,000 range together with an attractive bonus and benefits package.

Application Process

If you would like to join us as Manufacturing Manager at this critical time in our development and you think your skills and experience are a good fit for this role apply with a current CV and we’ll get back to you within a day or two.

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Senior Brand Manager - FMCG

Pets Choice

Blackburn, NW
2 days ago
Blackburn, NW
2 days ago

Job Title: Senior Brand Manger
Location: Blackburn
Salary: Competitive depending on experience
Job Type: Full Time, Permanent
The company is a leading pet food manufacturer whose industry knowledge spans over 135 years.
They have a portfolio of brands offering a variety of products for pets and wild animals, each offering a unique insight into animals from dogs to ducks and produces high-quality products that cater to a wide variety of consumer needs.
This is a fantastic opportunity for an experienced brand manager to join an exciting FMCG business developing, implementing, and executing strategic marketing and NPD plans for the pet food and treats category and associated brands.
The Role:
You'll work within the marketing team, reporting to the Head of Marketing. You will have a background in managing a small team, product and brand marketing, managing agencies as well as an ability to work alongside marketing, production and technical NPD teams to help increase the reach of the brand and products.
The role will focus on the pet food brands and as such the role will require involvement in events and shows around the country and occasionally abroad. It is essential that you're confident and comfortable around dogs and other pets.
Ideally coming from a manufacturing background, you will need to drive the product portfolio, working within a fast-paced environment, FMCG experience is essential, along with the ability to manage multiple projects simultaneously.
Key Responsibilities:
  • Lead pet food and treat brands
  • Manage and develop, two direct reports - Brand Managers
  • Brand strategy - including the setting of style guides, brand guidelines, brand vision and value proposition for short as well as long term
  • Develop the annual marketing plans and contributes to NPD/EPD pipeline ensuring excellence in execution
  • Develop brand portfolio strategy, contribute to pricing and promotional strategy recommendation, propose brand portfolio and reviews for key channels and key customers, aligning with sales
  • Work across functions including sales, the NPD team, technical, manufacturing, supply and finance to develop and contribute to execute successful commercial plans to deliver financial and share plans and targets
  • Responsible for packaging development and work with creative agencies and closely with Project Management Team
  • Develop brand content and campaign plans, implement and drive all marketing, advertising & promotional activities
  • Analyse product sales, market data and relevant financials
  • Maintain brand integrity across all company marketing initiatives and communications of products
  • Continuously monitor marketing trends and keep a close eye on competitive products & activity in the marketplace - supported by the Category & Insights team
  • Develop shopper marketing & category management initiatives to deliver the shopper brand experience at the point of purchase within the retail environment
  • Manage annual marketing budget

About you:
Essential
  • Master's degree in marketing or similar
  • Minimum of 2 years' experience working within an FMCG business is essential
  • At least 5 years' experience as a Brand Manager (or similar role) with knowledge and/or experience in shopper marketing and category management
  • Strong interpersonal skills with the ability to interface with and influence a diverse population, multiple levels of an organization and various cross-functions and multi-cultural teams
  • Strong analytics skills
  • Result oriented and able to manage multiple projects simultaneously
  • Direct line management
  • Problem solving
  • Positive / personable attitude always.
  • Very organised and reliable
  • Must be fluent in English
  • Full UK and clean driving licence is preferred

Desirable
  • Experience in the pet food/pet care or pharmaceuticals sector
  • Working within a manufacturing environment
  • Languages - Spanish, Germany, Italian or French

Please click on the APPLY button to send your CV and Cover Letter for this role.
Candidates with the relevant experience or job titles of; Brand Manager, B2C Marketing, Company Branding, Retail Marketing, Product Marketing, FMCG Brand Manager may also be considered for this role.
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Production Operative

Extra Personnel

Darwen, NW
6 days ago
Darwen, NW
£10.68 - £10.68 Per Hour
6 days ago
£10.68 - £10.68 Per Hour

Production Operative
Extra Personnel are recruiting on behalf of our large manufacturing client based in Darwen for the position of Production Operative.
There are opportunities to develop a career within the business
Requirements of a Production Operative
  • Be flexible to work 12 shifts covering days, nights and weekends
  • Previous experience working in a manufacturing environment

Details:
  • Salary - £10.68 per hour
  • Working hours of a Production Operative are 4 on 4 off, days and nights 12 hour shifts.
  • Overtime available
  • Location - Darwen
  • Duration - Ongoing
  • All suitable candidates will be subject to alcohol and drug testing at induction stage.
  • Extensive training will be given

Role of a Production Operative
  • Assembling and clamping the product
  • Working according to health and safety guidelines
  • Ensuring that the final products meet quality standards
  • To ensure all company procedures and rules are adhered to

Benefits of working in this role
  • Free On-Site parking
  • Canteen facilities
  • 28 days holiday per year
  • Canteen Facilities
  • Mortgage References
  • Personal Accident Insurance
  • Weekly Pay
  • Pension Scheme
  • Employed Status
  • My Resource Rewards - An online portal offering vouchers and discounts

If you are interested in the above role please click apply
Extra Personnel do NOT charge any fees for our services.
Extra Personnel Limited acts as an employment agency for permanent recruitment and employment business for the supply of temporary workers.
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Team Leader/Production Operative

Extra Personnel

Blackburn, NW
7 days ago
Blackburn, NW
£10.9 - £10.9 Per Hour
7 days ago
£10.9 - £10.9 Per Hour

Team Leader/Production Operative
Extra Personnel are recruiting on behalf of our large manufacturing client based in Blackburn for the position of Team Leader/Production Operative. As a Team leader you will be working closely with Extra Personnel to help with the management of their staff.
This will be a working role and the Team Leader will also be required to carry out day to day production duties.
Requirements of a Team Leader/Production Operative
  • Be flexible to work 8 hours shifts 6am-2pm, 2pm-10pm,(rotating each week)
  • Previous experience working in a manufacturing environment
  • Previous Team leader experience
  • Good Attention detail
  • Ability to work under pressure
  • First point of call for any agency staff issues
  • Checking in all agency staff at the start of each shift
  • Work closely with shift managers reporting any issues
  • Liaise with the agency with additional staff request
  • Good Communication skills

Details of Team Leader/Production operative:
  • Salary - £10.90 per hour
  • Working week Monday till Friday
  • Overtime available
  • Location - Blackburn
  • Duration - Ongoing
  • Accessible by public transport
  • Some lifting will be involved
  • Extensive training will be given

Role of a Team Leader/Production Operative
  • Machine operating
  • Working on the production line
  • Packing, trimming, cutting and palletising
  • Working according to health and safety guidelines
  • Ensuring that the final products meet quality standards
  • To ensure all company procedures and rules are adhered to

Benefits of working in this role as Production Operative
  • Free On-Site parking
  • 28 days holiday per year
  • Canteen Facilities
  • Mortgage References
  • Personal Accident Insurance
  • Weekly Pay
  • Pension Scheme
  • Employed Status

If you are interested in the above role please click apply and attach your CV
Extra Personnel do NOT charge any fees for our services.
Extra Personnel Limited acts as an employment agency for permanent recruitment and employment business for the supply of temporary workers.
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Production Operative

Extra Personnel

Darwen, NW
7 days ago
Darwen, NW
£10.68 - £10.68 Per Hour
7 days ago
£10.68 - £10.68 Per Hour

Production Operative
Extra Personnel are recruiting on behalf of our large manufacturing client based in Darwen for the position of Production Operative.
There are opportunities to develop a career within the business
Requirements of a Production Operative
  • Be flexible to work 12 shifts covering days, nights and weekends
  • Previous experience working in a manufacturing environment

Details:
  • Salary - £10.68 per hour
  • Working hours of a Production Operative are 4 on 4 off, days and nights 12 hour shifts.
  • Overtime available
  • Location - Darwen
  • Duration - Ongoing
  • All suitable candidates will be subject to alcohol and drug testing at induction stage.
  • Extensive training will be given

Role of a Production Operative
  • Assembling and clamping the product
  • Working according to health and safety guidelines
  • Ensuring that the final products meet quality standards
  • To ensure all company procedures and rules are adhered to

Benefits of working in this role
  • Free On-Site parking
  • Canteen facilities
  • 28 days holiday per year
  • Canteen Facilities
  • Mortgage References
  • Personal Accident Insurance
  • Weekly Pay
  • Pension Scheme
  • Employed Status
  • My Resource Rewards - An online portal offering vouchers and discounts

If you are interested in the above role please click apply
Extra Personnel do NOT charge any fees for our services.
Extra Personnel Limited acts as an employment agency for permanent recruitment and employment business for the supply of temporary workers.
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Multi-skilled Engineer / Electrical Engineer

Pets Choice

Blackburn, NW
2 days ago
Blackburn, NW
£35k - £36.5k Per Year
2 days ago
£35k - £36.5k Per Year

Job Title: Multi-skilled Engineer / Electrical Engineer
Location: Blackburn
Salary: £35,000 - £36,500 pa
Job Type: Full Time, Permanent - Shift Pattern: 4 on 4 off rotating across day and night shifts (no Saturday PM working)
This is a fantastic opportunity for a talented multi-skilled engineer with an electrical bias looking for a new challenge.
The company is a leading pet food manufacturer whose industry knowledge spans over 135 years.
They have a portfolio of brands offering a variety of products for pets and wild animals, each offering a unique insight into animals from dogs to ducks and produces high-quality products that cater to a wide variety of consumer needs.
Role Overview:
As a Multi Skilled Engineer you will be required to work closely with the production team maintaining and servicing all processing machinery across two sites to ensure that machinery downtime is kept to a minimum and that all preventative maintenance is conducted in advance to avoid production disruption. You will need to have worked in a similar manufacturing environment and be able to carry out preventative maintenance, fault finding and deal with machine down-time efficiently.
You'll rotate as part of a multi-disciplinary team working seven days a week across both day and night shifts (Saturday night shift is always off). Excellent communication skills are a must as well as a flexible and proactive approach to ensure the needs of the business are met.
Key Responsibilities:
  • As a Multi Skilled Engineer, you will work collaboratively within the engineering team
  • You'll action any repairs and ensure that all measures taken are recorded so recurrent faults can be recognised
  • You will be involved in electrical and mechanical proactive and re-active maintenance
  • You will carry out responsibilities in accordance with the organisation's policies and procedures
  • You will provide assistance in troubleshooting and identification of equipment problems
  • You will maintain relationship with operators to foster a good team environment when working on the equipment
  • You will be able to writes SOP's and other technical documents in support of the engineering department as well as the end users
  • Contribute to the continuous improvement of processes and practices
  • Conforming to company health and safety procedures and policies

Essential Requirements:
  • Must be fluent in English (verbal and written)
  • Time served electrical apprenticeship or equivalent
  • ONC/HNC in engineering or equivalent
  • Good experience and able to demonstrate a methodical approach to fault finding, including PLC's
  • Excellent I.T Skills
  • The successful candidate will hold a strong engineering background, ideally electrically bias with mechanical skills
  • Conversant with Health & Safety rules, regulations and best practices
  • Ability to prioritise workload and concisely record information
  • Knowledge of pneumatics and hydraulics.

Please note: due to the nature of the role, no sponsorship or relocation packages will be available for this position and so candidates must be eligible to both live and work in the UK to be considered.
Please click on the APPLY button to send your CV and Cover Letter for this role.
Candidates with experience of: Maintenance Engineer, Multi Skilled Engineer, Maintenance Technician, Site Maintenance Engineer, Service Engineer, Multiskilled Engineer, Field Service Technician, Service Technician, Electrical Engineer, Electrical Technician, Repair Engineer, Repair Technician and Fault Repair Engineer may also be considered for this role.
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Delivery Station Manager

Amazon UK

Manchester, NW
14 days ago
Manchester, NW
14 days ago
Delivery Station Manager 

Delivery Station Manager 


1376118
40hrs a week
We are Amazon: we pioneer.
Since opening our virtual doors in 1995, we’ve been pushing the boundaries of possible further and further.
Our entire business works hard to delight our customers – from the second an order is placed online to the seamless coordination of that order behind the scenes, we strive to stay agile, fluid and intentional. That can be described in one of our core Leadership Principles, which is Bias for Action. This means that our teams band together, roll up their sleeves, and aren’t content with just standing still. We’re aiming to become the most customer-centric company on Earth.
As we continue to grow, we are keen to speak to experienced operators. These fast-moving facilities sit at the heart of Amazon’s rapidly growing Operations network, and are where we manage our fast-moving parcels.
Delivery Station Manager Responsibilities:
Our Delivery Stations work as smart as they can to continuously delight our valued customers with their products: our top-line vision is to remove all effort on behalf of our end-users, while continuing to exceed everyone’s expectations whenever we can.
With this in mind, you’ll strategically lead a team, comprising of Operations Managers, Area Managers, Operations Supervisors and Operations Assistants. This will complement your proactive management of healthy, positive working relationships on a day-to-day basis.
In this role, you’ll work with key business partners, such as Transport & Sortation, DSP Management, Finance, Loss Prevention, IT, HR, ACES and Engineering. Furthermore, you’ll track and drive both the operational goals and metrics of your Delivery Station, while regularly presenting your findings to the senior leadership team.
Finally, you’ll also help us as we Hire and Develop the Best – that’s one of our key Leadership Principles, which you’ll come to know well. This will help you create and implement a talent plan for your site, and will touch on talent acquisition, performance and career management, learning and development and positive employee engagement.

Delivery Station Manager basic Qualifications:

  • Degree Qualification or equivalent.
  • Direct management experience, comprising both a salaried workforce, hourly and agency strong workforce, in a logistics, manufacturing, engineering, production or distribution environment.
  • Experience with planning, performance metrics, process improvement, and lean techniques.
  • Experience with the full staffing lifecycle, including interviewing, hiring, performance management, promotions, and terminations.
  • Strong analytical capability; track record of digging into data and finding solutions for a variety of operational problems.
  • Flexibility to work a variety of hours as business demands, including overnight, weekends and holidays.
  • Excellent communication skills (including local language and English, written and verbal).
  • Experience managing third party resources on a regional/national scale.
  • Experience managing contingent workforce in a business with peak season.

About our Rewards:
We’ll expect you to go the extra mile, but we’ll also make sure you’re well rewarded. As well as a competitive salary, stock units and site performance-related pay potential, we offer a whole host of other benefits, including an employee discount. Additionally, you will find yourself in a stimulating environment where you can develop processes as well as yourself as an individual by working with some of the best and brightest minds in the industry. Our rapidly growing organisation also offers many opportunities for building a diverse and rewarding career.
To apply for this Delivery Station Manager position, please click on the apply button!

Amazon is an equal opportunities employer. We believe passionately that employing a diverse workforce is central to our success. We make recruiting decisions based on your experience and skills. We value your passion to discover, invent, simplify and build. Amazon takes data protection seriously and respects EU and local data protection laws. Unless you express otherwise, by submitting your CV you authorize the hiring Amazon company to store your personal information in the electronic database maintained by Amazon Corporate LLC. in the USA or one of its affiliates for the purpose of assessing your suitability for this and future job vacancies and to pursue your recruiting process. If at any time you want your personal data to be deleted, you simply need to notify the hiring Amazon company. Amazon will not share your personal information with any third party without your prior consent. As part of your interview process with Amazon you may be asked to authorize the hiring Amazon company to separately verify your application data and personal background through a third party service provider.
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Assembly Operative

Extra Personnel

Horwich, NW
1 day ago
Horwich, NW
£10.22 - £12.05 Per Hour
1 day ago
£10.22 - £12.05 Per Hour

Assembly Operative
We are recruiting for the position of Production Operative in the Horwich area working for a leading manufacturing company.
Role and responsibilities of Assembly Operative :
  • Quality control - highlight quality issues
  • Electrical Assembly
  • Working towards targets and KPI's
  • Follow procedures
  • Team Working

Experience preferred for Assembly Operative
  • Good levels of English
  • Excellent attention to detail
  • Mechanical & Electrical knowledge
  • Can do attitude towards work

Details
  • Working hours: Rotating 6am -2pm / 2pm-10pm / 10pm-6am shifts
  • Pay Rate - £10.22 per hour rising to £12.02 per hour
  • Ongoing positions
  • Permanent positions available for excellent candidates

Benefits of working with us as an Assembly Operative :
  • 28 Holidays per year
  • Weekly Pay
  • Pension Scheme
  • Onsite Car Park
  • Employed Status
  • Personal Accident Insurance
  • Mortgage references
  • My Extra Rewards- An online portal offering vouchers and discounts

Job Types: Full-time, Temporary, Permanent
Salary: £10.22-£12.02 per hour
Extra Personnel do NOT charge any fees for our services.
Extra Personnel Limited acts as an employment agency for permanent recruitment and employment business for the supply of temporary workers.
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Manufacturing Manager

Applicant Services

Manchester, NW
7 days ago
Manchester, NW
£42k - £43k Per Year
7 days ago
£42k - £43k Per Year

This could be your chance to work for a nationwide respected Heat Treatment company! Established in 1974, our client is one of the UK's leading Heat Treatment engineering companies. 

MANUFACTURING MANAGER (Heat Treatment Systems)

£42,500 per annum + 25 days paid annual leave

This progressive heat treatment equipment manufacturing company are looking to recruit a Manufacturing Manager for their Wigan works.

The successful candidate will be based out of our office in Wigan, working Monday to Friday 08:00 - 17:00hrs. Primary day to day duties of this role will include but not be limited to:

Primary day to day duties of this role will include but not be limited to:

  • Daily management of the manufacturing employee’s workload, currently a team of six.
  • Purchase order processing.
  • Sales order processing.
  • Overlooking stock control.
  • Liaising with shipping companies with regards to importing and exporting of goods.
  • Setting up of new products on our system.
  • Setting up and maintaining bills of materials.
  • Dealing with customer enquiries.
  • Dealing with supplier enquiries.
  • Reading engineering drawings.
  • Creating engineering drawings.
  • Maintaining and keeping up to date the training records relating to the manufacturing employees.
  • Collating the weekly hours and forwarding this information to payroll to enable the weekly wages to be processed.

About you

The ideal candidate will be from an engineering background and preference will be given to applications that demonstrate experience of AutoCAD and Sage 200.

You will also need to demonstrate effective leadership skills coupled with excellent time management and organisation ability.

How to apply for the Manufacturing Manager job

Click “apply” for your new career now! Watch out for an email giving you more information on how to tailor your application and provide a cover letter or any other supporting documents you may have.

You must be eligible to work in the UK

Suitable skills and experience include production manager, production leader, manufacturing leader, mechanical engineering management, engineering manager, heating and mechanical manager, thermal engineer manager.

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Manufacturing / Fabrication Draughtsperson

GPW Recruitment

Rochdale, NW
7 days ago
Rochdale, NW
£35k - £45k Per Year
7 days ago
£35k - £45k Per Year

We are looking for a Manufacturing / Fabrication Draughtsperson with architectural metalwork and secondary steelwork experience for a temporary to permanent position in the Rochdale area. Pay rate of £35-45000 per annum depending on experience. There are opportunities to work from home during the pandemic.
Working as the successful Manufacturing / Fabrication Draughtsperson, you will not be designing, but you will be developing out Architect and Structural Engineering drawings and providing manufacturing drawings for operations. You need excellent Architectural Metal experience and good 2D AutoCAD experience. If you also have 3D skills as well this would be an advantage - AutoCAD 3D, Solidworks, Tekla or similar - but it is not essential.
The Manufacturing / Fabrication Draughtsperson position is not highly technical work. It could suit either an experienced Draughtsperson or someone with workshop/hands-on welding and fabrication experience and CAD ability who is looking to change direction slightly and produce the manufacturing drawings now rather than do the fabrication. You will have experience of things such as handrails, balastrades and staircases. You will go to site, measure up then produce the drawings.
Previous Contract Engineer or similar experience would be highly desirable. The role includes a watching brief over the full process from survey through to installation of metalwork with worksites around the UK.
Main roles, responsibilities and requirements:
*Create 2D drawings and/or 3D Models to create Fabrication Packages.
*Occasional site survey visits (vehicle supplied for work purposes).
*Liaise with other areas of the business to ensure projects are completed on time.
*This is not highly technical work, the successful candidates will have a background in general fabrication and Engineering.
*Most important is the drive and desire to move forward in your career.
*CAD software skills.
*Experience in a Contract Engineer or similar role is highly desirable.
The company we are recruiting this Manufacturing / Fabrication Draughtsperson for is a market leading company who design, manufacture and install high quality bespoke items. They are doing very well and the successful Manufacturing / Fabrication Draughtsperson will have excellent career prospects and will help deliver a very busy and expanding order book
If the above sounds like you, please apply now!

Posted

22 days ago

Description

About Instil Bio

Instil Bio is a cell therapy company developing tumor infiltrating lymphocytes (TIL) for the treatment of solid tumor cancers. TIL are a patient’s own T cells harvested from the patient’s tumor, which are then expanded and reinfused into the patient to target and kill cancer cells. Instil is advancing its proprietary TIL manufacturing expertise, technology, and data into clinical trials, including a planned registrational study with its lead candidate and a first-in-human study of its next-generation engineered TIL. The company is led by world-class cell therapy experts and backed by premier global institutional investors.

Instil Bio UK is Instil’s rapidly-growing, Manchester UK-based subsidiary. Our Manchester subsidiary has significant R&D, process development, and clinical manufacturing capabilities, with approximately 35 staff expanding to > 100 staff. Instil Bio UK has been generating cell therapy products for patient use since 2011, including TIL products and external partner genetically engineered T cell products.

Manufacturing Manager – Cell Therapy

Instil Bio UK is now recruiting a Manufacturing Manager, responsible for supporting the Director of Manufacturing (UK) in building, training, managing and mentoring manufacturing staff within the Manufacturing function at Instil Bio (UK)’s clinical manufacturing facilities in Manchester, UK. You will be responsible for leading, developing and managing staff to manufacture batches to meet clinical demand, achieve improvements in planned aseptic manufacturing production, pharmaceutical awareness, cGMP, capacity utilisation, quality, cost and supply plans and activities in compliance with company, regulatory, pharmaceutical standards.

As the Manufacturing Manager you will be required to: 

•    Support the Dir. Of Manufacturing in strategic planning and leadership to meet site and global objectives. 

•    To recruit, train, develop and coach technical team members such that increased focus is put on pharmaceutical awareness and operating standards as well as job skills and knowledge of an advanced therapy medicinal product (ATMP)

•    Ensure manufacturing operations adhere to regulatory requirements (US, UK, and EU) 

•    Work with QC and QA to ensure on-time product release per specification 

•    Work with supply chain to plan production schedules, receive material and execute on-time product manufacturing 

•    Through implementation of Continuous Improvement philosophy, manage and improve pharmaceutical standards, awareness & compliance within the technical team (measures: CAPA close out, NCR close out, clean room standards, engineering standards); 

•    Implement operational excellence principles to ensure accelerating manufacturing cadence meets clinical targets 

•    Setting, communicating, tracking, and reporting KPI’s at a personal and departmental level 

•    Champion a continuous improvement culture; work cross-functionally with Manufacturing Sciences and Technology (MS&T) and Quality to improve manufacturing operations in a compliant manner 

•    Work cross-functionally on new product introduction and process changes (transfers, improvements, validation) 

•    Ensure processes are followed for change controls, deviations/investigations, CAPAs, process transfers, validations, risk analysis, and mitigations

The role is not required to be on a shift pattern but will require establishing multiple teams and shifts to deliver product through clinical trial according to targets. Flexibility may be required to take calls or do some work from home outside normal business hours.

Relevant Education Skills and Experience

This role will involve hiring and building teams along with team management. It will involve developing and leading other manufacturing and manufacturing support staff. To be successful it is anticipated you will have gained the following skills, traits, and experience:

•    Team management and people development. Ability to successful manage manufacturing operations through good planning and resourcing. Eye for detail to ensure right first-time operational excellence.

•    At least 5 years of experience managing operational teams Managing at least 12 staff. Experience of implementing strategic decisions through organised teams. Experience representing manufacturing on large multi-disciplinary project teams 10+ years relevant GMP aseptic cell culture manufacturing experience (e.g. cell therapy, gene therapy, biologics, vaccine)

•    BS degree in life sciences, engineering or related field, advanced degree, e.g. MS, MBA, and/or PhD preferred Quality Systems used in GMP environments Knowledge of GMPs and compliance within the biopharmaceutical industry

•    A target driven team builder who enjoys working in a fast-paced environment

•    Detailed planning and resource management Very good communication and interpersonal motivation skills Ability to accommodate flexible working hours depending on work nee

The following experience may be considered an advantage but is by no means essential to a successful application:

•    Guidance and compliance with MHRA, HTA, European Directives or FDA guidance for Cell Therapies

•    Experience in cell therapies/ATMPs 

•    Experience with managing shift working

Remuneration & Benefits

The salary for the Manufacturing Manager will be competitive within the Biotechnology and wider Scientific sector with actual salary offered reflecting relevant qualifications and experience as well as performance at interview. In any event we anticipate a salary in the £45,000 to £55,000 range together with an attractive bonus and benefits package.

Application Process

If you would like to join us as Manufacturing Manager at this critical time in our development and you think your skills and experience are a good fit for this role apply with a current CV and we’ll get back to you within a day or two.

Source: Instil Bio