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3869 Jobs Found 

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Supply Chain Associate Director

TCR² Therapeutics

9 days ago
9 days ago

TCR2 Therapeutics Inc. is a clinical-stage immuno-oncology company developing the next generation of novel T cell therapies for patients suffering from cancer. Our proprietary TRuCâ„¢ (TCR Fusion Construct) T cells harness the natural T cell receptor complex to recognize and kill cancer cells using the full power of T cell signalling pathways independent of HLA. TRuC-T cells have demonstrated superior anti-tumor activity in vivo compared to CAR-T cells while releasing lower levels of cytokines in preclinical studies.  TCR2 was founded by MPM Capital and is headquartered in Cambridge, MA to leverage best-in-class technologies and nucleate top-tier academic laboratories from around the world.

 

TCR2 has embarked on establishing a cGMP manufacturing operation in the UK at Stevenage, Hertfordshire, to provide manufacturing capacity for Phase 1 and Phase 2 operations, and beyond, for the TRuCTM T cell platform. The Supply Chain Manager will report to the VP of Manufacturing and will be responsible for the logistics of patient material in the UK, manage our Third Party Logistics organisations as well as planning, purchasing, storage and movement of materials for clinical GMP manufacturing. This position offers an exciting opportunity to join the Stevenage team at an early stage, to deliver life saving therapies to cancer patients across a broad class of indications. 

 

 

Responsibilities:

  • Lead the Supply Chain team and manage the supply chain requirements for manufacturing in a compliant and efficient manner to meet clinical schedules
  • Support the scheduling of clinical batches from and back to US clinical centres using approved clinical logistics software systems
  • Manage UK logistics for clinical material and finished products with approved shipping providers to meet GMP, HTA and import/export licensing requirements
  • Coordinate with the manufacturing team and CGT Catapult warehouse to schedule picking of inventory for manufacturing
  • Manage local KanBan systems for the manufacturing module to ensure supplies are maintained at an optimal level for production operations
  • Provide a centralized purchasing function for all GMP materials for production and QC and support any non-GMP purchasing as required
  • Manage 3PL relationships and provide oversight to ensure all materials are received, stored and shipped in a GMP compliant and timely manner
  • Implement improvement programs internally, at 3PLs and at CGT Catapult to reduce lead times and costs for materials management and handling
  • Oversee Sage inventory management systems at CGT Catapult and 3PL suppliers to support manufacturing and to maintain compliance to policies and procedures
  • Work with the TCR2 Finance team and report on UK inventory levels to meet financial planning and compliance requirements   
  • Manage supplier relationships to provide high levels of supply excellence in terms of cost, quality and on time delivery
  • Develop and report key performance indicators, KPIs, for supply chain operations, both internally and with external suppliers and service providers

 

Qualifications and Experience:

  • Bachelor’s degree in a Supply Chain, Logistics or related field, or a CIPS or CILT accreditation
  • A minimum of 8 years progressive experience in pharmaceutical, biotech, or biologics supply chain and logistics, with cold chain experience
  • Working knowledge and ability to apply GMPs in conformance with FDA, MHRA, EU and ICH standards for supply chain and logistics operations 
  • Experience and involvement in external regulatory inspections an advantage
  • Ability to effectively negotiate and build collaboration with 3PLs, service providers and suppliers
  • Good interpersonal, verbal and written communication skills
  • Comfortable in a fast-paced small company environment with minimal direction.

 

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H
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Upstream scientist

Hyper Recruitment Solutions

East Anglia, ANGL
6 days ago
East Anglia, ANGL
6 days ago
We are currently looking for a Upstream scientist to join a leading Cell and Gene Therapy company based in the South East . As the Upstream scientist you will be responsible for the upstream processes of GMP manufacturing batches.
This is an exciting opportunity for an experienced Biologics Manufacturing scientist to join leading company focused on the development and production of life saving therapies.
KEY DUTIES AND RESPONSIBILITIES:
Your duties as the Senior Manufacturing Technologist will be varied however the key duties and responsibilities are as follows:
1. Lead and Support the production of Biological products under GMP conditions where you will be responsible for the writing and updating of SOPs as well as batch records.
2. You will use cutting edge Bioprocessing equipment including pilot and large-scale Bioreactors and Single Use Bioreactors ( SUBs ) for the upscale of mammalian cell and viruses.
3. You will be an equipment owner responsible for leading the equipment during manufacturing as well as training and delegating use to junior members of staff. You will also troubleshoot issues and ensure servicing is maintained.
4. You will be apart of the Upstream Processing ( USP ) team and will be hands on with aseptic cell culturing for seed train expansion prior to USP.
ROLE REQUIREMENTS:
To be successful in your application to this exciting opportunity as the Upstream Scientist we are looking to identify the following on your profile and past history:
1. Relevant degree in a Life Sciences discipline (e.g. Biology, Biochemistry, Molecular Biology, Biotechnology etc.) in addition to previous experience in a GMP Manufacturing environment where you have produced Biopharmaceuticals in Upstream Processing. Experience of manufacturing investigational medicinal products would be beneficial.
2. Proven industry experience using Single Use Bioreactors ( SUB ) as well as pilot scale or large scale Bioprocessing equipment in a GMP environment.
3. A working knowledge and practical experience with Upstream Processing where you have experience of Cell Culture, Seed Train, SUBs and Depth Filtration.
Key Words: Manufacturing Technologist | Production Technologist | Biotechnologist | Upstream Processing | USP | Bioreactor | Bioprocessing | Biologics | ATMPs | Viral Vectors | GMP | Good Manufacturing Practise | Cell Culture | Single Use Bioreactor | SUB | Cell and Gene therapy | South East | Upstream Processing | Upstream | Wave bag
Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer who are certified by Investors in People for talent development. We therefore welcome applications for any interested parties who fulfil the role requirements for this position. HRS is a company exclusively supporting the science and technology sectors, and is made up of a collaboration of recruitment professionals and scientists. We look forward to helping you wit
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Project Manager - Food Manufacturing - Edinburgh

Focus Management Consultants Ltd

Edinburgh, Scotland
6 days ago
Edinburgh, Scotland
£45k - £50k Per Year
6 days ago
£45k - £50k Per Year

Excellent opportunity for a Project Manager to join a market-leading FMCG business in Edinburgh, Scotland
My client Is a multisite blue-chip business that is known for offering training and development, and because this role is based at such a large site, the operational structure means that career progression is very realistic too.
As Project Engineering Manager you will lead the initiation and delivery of capital expenditure projects across the site.
Projects will be varied, and you will often be working on several projects at the same time; Projects will include but not be limited to - equipment installation, construction, refurbishment, packaging, energy, waste, water, continuous Improvement, etc.
You will be the engineering lead on all scoping, design, and project delivery of capital projects, working with several departments across the site.
You will be a logical thinker and a natural problem solver, who has the confidence and conviction of presenting to the leadership team, new ideas, and initiatives to help improve business and process.
To be considered for this role it is essential you have an engineering degree or equivalent and have relevant Engineering and Project management experience within food manufacturing/FMCG, ideally, you will be IOSH qualified and have Prince2 project management.
This is a Monday to Friday days-based position.
If this sounds like a business, you would like to be part of and you think you have the right skillset and attributes then please apply.
Ref DJF895802
+44 (0)1625 560778
Twitter @foodjob
Instagram @focus_recruitment
Linkedin @Focus Management Consultants
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HRBP, Food Manufacturing, Lincolnshire

Focus Management Consultants Ltd

Lincolnshire, MID
2 days ago
Lincolnshire, MID
£54k - £56k Per Year
2 days ago
£54k - £56k Per Year

This is an extraordinary role for an extraordinary business.
Straight up disclaimer: this is a busy role. Speaking to one employee, they had had a roller coaster of a week by 8.45am on Monday morning. So this won't be for the faint hearted. But then again, you've worked in FMCG/Logistics/Food Manufacturing before so you aren't expecting an easy ride.
And roller coasters are fun. So is recording 80% growth YoY in Q1 this year and believe it or not, that figure has actually increased since.
This company claims they are the future of food and they have two compelling reasons why.
  1. Their route to market
  2. Their utilisation of data

If you are a modern thinking in the broadest sense and looking for better ways of doing things, this is the role & company for you.
You will need to have experience in a similar sector and be CIPD qualified. However, more than anything high energy is what every employee shares in this company and for good reason, there is so much to do (thanks to the insight driven by point 2 above).
They believe they are the future, do you see yourself being part of it? If you think you do, apply now.
REF: DAC895687
Tel: +44 (0)1625 560778
Twitter @foodjob
Instagram @focus_recruitment
Linkedin @Focus Management Consultants
E
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Manufacturing Technician

Eden Scott

6 days ago
6 days ago

Due to continued growth, my client who is a well established manufacturing organisation based in West Lothian, area are looking for Manufacturing Technicians on a permanent basis. The role will see you execute defined and trained manufacturing steps for the production of JEV according to set procedures and protocols and according to best cGMP work practices and Quality standards

Key responsibilities:

  • Execute production steps defined by SOPs, production records and protocols
  • Apply best cGMP work practices and techniques
  • Conduct on-time reporting according to defined document management standards
  • Immediately escalate and report any deviations to materials, facilities, processes or procedures to the supervising team
  • Be accountable that the individual workspace is clean, tidy and well organised
  • Conduct all activities in the most careful and safe manner and in full compliance with HSE requirements
  • Ensure that at any time equipment, facilities and materials used in the area of responsibility comply with defined standards
  • Support change controls, investigations and CAPAs in the most diligent manner
  • Identify areas for continuous improvement and escalate those to the respective manufacturing supervisor or appropriate person
  • Actively contribute to the development and maintenance of an enthusiastic, supportive and collaborative environment within the team setting
  • Shift work and out of hours work as required
  • To undertake any other duties as requested by the line manager in accordance with company requirements

Experience:

  • Relevant degree or HNC/HND or equivalent experience
  • Experience of working within a cGMP environment
  • Experience of following SOPs within defined cGMP work practices
  • Excellent comportment in Cleanroom environment
  • Good attention to detail and adherence to procedures
  • Ability to execute activities following direction
  • Experience of working in a busy team and demanding environment

Apply now for more information

 

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VP Manufacturing Engineer-Civil

GKN

London, London
8 days ago
London, London
8 days ago

The VP Manufacturing Engineering leads the ME function in the Business Line and has complete responsibility for managing the whole product lifecycle from an ME perspective. They are accountable for developing, delivering, sustaining and continually improving manufacturing engineering solutions for Programs & Operations. This scope extends from process technology insertion, to Bid & Proposal, New Product Introduction and Serial Production support. The role will focus on strengthening industrial capability by leading deployment of global standards across the operating sites and Program IPTs. They are accountable for delivering NPI Programs to a Zero Defect Manufacturing (ZDM) standard, on-time and on budget to ensure realization of the Program Business case. They are also accountable for delivering annual quality improvement through deployment of a ZDM & problem solving culture and tool suite(s).

Job Responsibilities

Accountable for technical leadership of the ME function within Operations supporting the Business Line. Complete, end-end ownership of all manufacturing engineering responsibilities across the product lifecycle
Accountable for developing and deploying global ME standardisation across operating sites and IPT team
Accountable for delivering New Product Introduction Programs to a Zero Defect Manufacturing (ZDM) standard, on-time and to budget to guarantee Program business case is met
Accountable for delivering annual quality improvement targets, enabling year on year conversion cost reduction
Accountable for compliance to process across sites within the region including leading and driving industrialization governance standardisation and compliance across all NPI Programs in accordance with the Lifecycle Gate Process. Ensures that all aspects of new business acquisitions/proposal development are compliant with the commercial bid governance process with particular focus on summarizing/quantifying Risk to the business from a Product Quality perspective
Accountable for developing and deploying the Zero Defects Manufacturing (ZDM) mind-set and culture into the ME organisation through implementation of standard ZDM tool suite and APQP process
Responsible for pulling technology into operating sites to solve operational problems and capitalize on opportunities
Responsible for acting as the senior technical voice to the Customer / 3rd parties on escalated technical & quality issues as required
Responsible for collaborating with other members of the Global ME leadership team on sharing and adoption of best practices through the establishment of Centres of Competency
Links closely with other VP Manufacturing Engineering to ensure resources are shared and deployed to NPI & Serial Production Programs in the most appropriate and efficient manner to support the overall business

Required Qualifications:

Bachelor Degree in Engineering
8 years of leadership level experience with business processes, cost responsibility, and complex engineering technical responsibility within the aerospace industry
8 years of experience in Operations and of Operational Engineering leadership
Experience of Continuous improvement and LEAN methodologies

P
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Shift Manufacturing ERP Team Lead

Pepsi Co

Cupar
1 day ago
Cupar
1 day ago
Auto req ID: 229360BR

Job Description

PepsiCo products are enjoyed by consumers more than one billion times a day in more than 200 countries and territories around the world. PepsiCo generated more than $68 billion in net revenue in 2020, driven by a complimentary food and beverage portfolio that includes Walkers, Gatorade, Pepsi-Cola, Quaker and Tropicana. PepsiCo's product portfolio includes a wide range of enjoyable foods and beverages, including 22 brands that generate more than $1 billion each in estimated annual retail sales.
Guiding PepsiCo is our vision to Be the Global Leader in Convenient Foods and Beverages by Winning with Purpose. “Winning with Purpose” reflects our ambition to win sustainably in the marketplace and embed purpose into all aspects of the business. For more information, visit www.pepsico.com.
The job holder is responsible for optimising the shift teams adoption and use of PGT across the MTD value stream as well as actively completing PGT transactions alongside principle PGT Role holders, ensuring all PGT transaction required by the shift teams are completed to the right standard and at the right times to ensure Plant performance is not impacted by PGT adoption.
PRINCIPAL ACCOUNTABILITIES

  • Supports PGT knowledge and usage adoption across the shift teams
  • Provides in the moment training and coaching around PGT
  • Provides top training as required to shift teams
  • Completes PGT transactions to support workload and managing plant efficiency where required
  • Ensure all shift PGT transactions are completed to standard and on time
  • Escalation point for PGT issues as first point of contact, able to resolve user issues based on PGT knowledge or escalate where a more critical gap or issue identified eg – Master Data error
  • Supports data creation via PGT for the 4 hourly QCDM meetings coaching behaviours and ensuring gaps are clearly understood, actions assigned, prioritised and escalated in a timely manner.
  • Ensures problem solving tools are applied as appropriate to address gaps identified through QCDM forums
  • Is accountable for ensuring all feedback regarding escalation is shared back to the relevant zone.
  • Holds Zone owners accountable for ensuring actions that effect PGT performance are closed out.
  • Escalates as required service, performance and behavioural concerns on shift to SOM
  • Carry out investigations on shift regarding safety, quality, performance and people where required
  • Work closely with the whole shift leadership team to ensure efficient plant performance and delivery to the right standard at the right time to maximise service delivery
  • Responsible for ensuring safety is a priority on shift and driving our safety culture through coaching and leadership on shift
  • Developing team through training and performance management
  • Actively supporting shift talent development and pipeline succession planning

Qualifications/Requirements

  • Strong capability to manage through influence and hold others to account
  • SAP knowledge and experience ideally Super user level
  • Experience in a manufacturing environment
  • Good analytical skills
  • Understanding of SAP/PGT processes, in particular MTD workstream
  • Strong Team worker and contributor.
  • Flexible, ‘can do’ attitude to role and duties.
  • Results driven and understands the link between action & results.
  • A good coach and communicator with individuals at all levels.
  • Excellent computer skills (Windows, SAP, Excel)
DECISION-MAKING AUTHORITY
  • Responsible for taking decisions that will drive improved plant performance via PGT and escalating where required (Safety, IPS, QCDM, Problem solving, Service impacts)
  • Responsible for identifying, addressing and escalating where required people performance issues

Relocation Eligible: Not Applicable
Job Type: Regular
We are an equal opportunity employer and comply with the Equality Act 2010, we value diversity at our company; it is an essential part of our success. We do not discriminate on the basis of age, pregnancy or maternity, marital/civil partnerships, religion or belief, sex or sexual orientation, gender or gender reassignment, disability or race including; colour, nationality, ethnic or national origin.

O
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General Manager

Oceaneering International, Inc.

Rosyth, Scotland
8 days ago
Rosyth, Scotland
8 days ago

General Manager assumes site leadership responsibilities at Director level in order to deliver the right working culture in all areas including safety, quality, performance, engagement, teamwork, collaboration, development, efficiencies, best practices, continual improvement/learning and finance in order to deliver business success required. They will be responsible for the safe and efficient running of the business and be accountable for the performance, behaviors and oCompanyomes of all direct/indirect reports while also ensuring best utilisation of current and future resources.  They will ensure and support successful cross-departmental and business collaboration in order to deliver KPI`s and business oCompanyomes required, participate in and support senior leadership teams/functions, stand in as/when required plus support and be part of business succession planning.  

Duties & Responsibilities

Functions

ESSENTIAL

To effectively perform all aspects of Leadership and general management, in particular the following
*Manages senior managers.
*Executes short to medium-term operational planning for sub-function.
*Applies functional knowledge across sub-functional groups and has practical experience in leadership and
management techniques.
*Investigates solutions to root causes of numerous undefined problems, and makes improvements.
Implement standard Uniform Project Management procedures and a continuous project management improvement culture.
Oversee the rejuvenation of manufacturing, creating a mindset of “execution,” correcting bottlenecks, addressing supply chain issues and getting deliveries back on track.
Create a good balance between managing by the numbers and creating a congenial caring work environment that highly values people.
Focus on project management by improving customer relations, project cost, schedule control, contract management, and risk management.
Develop a new strategic road map for the business that anticipates the need for increased productivity, capacity and demand in the near future.
Oversee the creation of a systematic, disciplined approach to contract reviews, bids and proposals.
Instill a positive “can-do” attitude into every section of the business, while creating a strong, positive atmosphere of teamwork and empowerment throughout the business.
Oversee the development of a leading-edge culture of safety and health practices throughout the business.
Seriously advocate a strong culture of continuous improvement and Lean Manufacturing, with a rigorous 5S mindset.
Identify huge opportunities of waste takeout, while developing the same proactive mindset throughout the organization.
Oversee the development of a comprehensive and rigorous toll gate system for project scheduling and management to insulate projects against delays.
Be a strong team builder, who instills a high sense of urgency and confidence throughout the organization.
Understand the magnitude of decisions and ensure that contracts have favorable terms and develop the same approach in staff.
Upgrade, educate, train and evaluate staff to work more cohesively as a team and communicate more effectively across the enterprise.
Measure productivity and instill discipline and accountability by utilizing appropriate metrics.
Will be culturally aware and exhibit a patient, caring, but firm, leadership style.
Become known as both a “Leader of People and Processes.”
Carries out supervisory responsibilities in accordance with the organizations policies and applicable laws.  Responsibilities include interviewing, hiring, and training employees; planning, assigning, and directing work; appraising performance; rewarding and disciplining employees; addressing complaints and resolving problems.
Contribute to the development and implementation of annual and strategic plans for the region.
Support and be responsible for the delivery of annual budget forecast with respect to revenue and profit & loss.
Top tier leader in the development of people and teams to ensure maximization of career development & talent potential, facilitate succession planning and change management strategy.
Ability to engage effectively with key internal and external stakeholders.
Eliminate waste of whatever form, to suggest the use of more environmentally friendly sCompanytances and practices and contribute to the continuous improvement of the environment.
Perform the assigned tasks with due diligence regarding the Integrated Management Systems on the Company.
Identify, create, establish and/or enhance effective partnerships both internally and externally as required.
Become known as both a “Leader of People and Processes.”
Displays required levels of engagement and a positive `can-do` attitude while consistently supporting Company culture of Safety, Quality, ongoing learning and continual improvement.
Carry out work in accordance with the Company Health, Safety, Environmental and Quality Systems.
Perform the assigned tasks with due diligence regarding the Integrated Management Systems and all other  Company standards.
Any other roles or tasks as required to support our business needs.
Supervisory Responsibilities
This position supports the Vice President in the leadership and supervision of direct reports including site Senior Management Team (SMT) and relevant department leaders.
This position also interacts with all functional support/shared services, some of whom are site based and for whom there will be matrix management responsibilities (dotted line), including HSEQ, HR, Talent Acquisition, Benefits, Global Mobility, Finance, Contract, IT and Legal.

Qualifications

Qualifications (Equivalent acceptable experience will also be considered in respect of below)
Possess superior business and management acumen, combined with at least fifteen, or more, years of experience.
Have an undergraduate degree; an MBA is a plus.  Post graduate business and/or professional qualifications welcomed
Experience
Have experience working in an engineered-to-order, high-value, low-volume, capital goods manufacturing environment.
Possess the experience required to drive world-class business and manufacturing practices.
Possess a broad understanding of the total business cycle and be aware of the risks associated with each business decision.
Exhibit a broad understanding of manufacturing, cost, quality, and delivery and project management, and possess the ability to drive major improvements in each category.
Demonstrate a strong command of business financials.
Be strategic in nature, yet possess the management skills to execute tactically.
Exhibit excellent communication and influencing skills.
Be a Coach, Mentor and Team builder, focused on building strong relationships across all levels of the business.
Drive cultural and operational improvement.
Significant experience in similar role running a business or business unit with full P&L responsibility in the manufacturing/energy sector essential.
Knowledge, Skills, Abilities, and Other Characteristics
To perform the job successfully, an individual should demonstrate the following competencies
Integrity Believes in conducting business honestly and respectfully with customers, team members, suppliers, and the communities they operate in.
Vision  Highly strategic in thought and behavior, driving daily execution while anticipating obstacles and opportunities and maintaining a long-term, big picture view. Possesses superior intellectual agility, dealing comfortably and quickly with complex manufacturing issues.
Change Agility An experienced change leader; creates effective plans to promote change; knows how to manage in changing cOrganizationumstances; seizes opportunities.
Drive for Results Results-oriented leader who can be counted on to exceed goals successfully; is constantly and consistently one of the top performers; sets defined, measurable expectations and provides employees with the resources to exceed them; very bottom-line oriented; steadfastly pushes him/herself and others for results.

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Project Manager - Food Manufacturing - Cornwall

Focus Management Consultants Ltd

Cornwall, SW
2 days ago
Cornwall, SW
2 days ago

A great opportunity for someone with first class Project Management skills in a commercial/purchasing arena to join a leading multi-site manufacturing business in a key role on the site leadership team.
My client is a leading chilled food manufacturing business operating across multiple sites in the UK. They have a great reputation in their market for the quality and innovation of their products and integrity in how they operate.
The business has recently gone through an exciting change in how they buy which has resulted in exciting new roles within the Business. They are now looking for an experience food manufacturing professional who will be a key part of the site leadership team and work in partnership with Group Procurement, Suppliers and Customers to protect the business from risk and transform supplier led innovation. You will own the purchasing agenda for your site and will have responsibility for planning and delivering the site PPV and PIP whilst being accountable for all supplier performance at your site.
A key part of the role will be ensuring that central procurement delivers the strategic and operational needs and that central projects are effectively managed through site. You will act as the site point of escalation for all procurement issues and ensure NPD have the right approved suppliers and are only using the correct approved suppliers.
I am looking for someone with experience of working in a food manufacturing environment in a Project Manager, Purchasing, Commercial or Supply Chain role and ideally be CIPS qualified. You will have driven through step changes within a business and be able to show how you did that. You will need to demonstrate the ability to deliver the highest performance standards. The ability to make difficult decisions and to take a calm and measured approach in an often-pressured environment, which often involves working to tight deadlines, to overcome and achieve results will also be vital.
The desire to succeed; and a positive "can do" attitude that positively influences the wider peer group and senior managers along with highly effective communication and presentation skills are key.
A full driving licence and a flexible approach to travel is essential in this role.
To apply please send your details through to me today.
Ref HLJ895765
Twitter @foodjob
Instagram @focus_recruitment
Linkedin @Focus Management Consultants

Posted

9 days ago

Description

TCR2 Therapeutics Inc. is a clinical-stage immuno-oncology company developing the next generation of novel T cell therapies for patients suffering from cancer. Our proprietary TRuCâ„¢ (TCR Fusion Construct) T cells harness the natural T cell receptor complex to recognize and kill cancer cells using the full power of T cell signalling pathways independent of HLA. TRuC-T cells have demonstrated superior anti-tumor activity in vivo compared to CAR-T cells while releasing lower levels of cytokines in preclinical studies.  TCR2 was founded by MPM Capital and is headquartered in Cambridge, MA to leverage best-in-class technologies and nucleate top-tier academic laboratories from around the world.

 

TCR2 has embarked on establishing a cGMP manufacturing operation in the UK at Stevenage, Hertfordshire, to provide manufacturing capacity for Phase 1 and Phase 2 operations, and beyond, for the TRuCTM T cell platform. The Supply Chain Manager will report to the VP of Manufacturing and will be responsible for the logistics of patient material in the UK, manage our Third Party Logistics organisations as well as planning, purchasing, storage and movement of materials for clinical GMP manufacturing. This position offers an exciting opportunity to join the Stevenage team at an early stage, to deliver life saving therapies to cancer patients across a broad class of indications. 

 

 

Responsibilities:

  • Lead the Supply Chain team and manage the supply chain requirements for manufacturing in a compliant and efficient manner to meet clinical schedules
  • Support the scheduling of clinical batches from and back to US clinical centres using approved clinical logistics software systems
  • Manage UK logistics for clinical material and finished products with approved shipping providers to meet GMP, HTA and import/export licensing requirements
  • Coordinate with the manufacturing team and CGT Catapult warehouse to schedule picking of inventory for manufacturing
  • Manage local KanBan systems for the manufacturing module to ensure supplies are maintained at an optimal level for production operations
  • Provide a centralized purchasing function for all GMP materials for production and QC and support any non-GMP purchasing as required
  • Manage 3PL relationships and provide oversight to ensure all materials are received, stored and shipped in a GMP compliant and timely manner
  • Implement improvement programs internally, at 3PLs and at CGT Catapult to reduce lead times and costs for materials management and handling
  • Oversee Sage inventory management systems at CGT Catapult and 3PL suppliers to support manufacturing and to maintain compliance to policies and procedures
  • Work with the TCR2 Finance team and report on UK inventory levels to meet financial planning and compliance requirements   
  • Manage supplier relationships to provide high levels of supply excellence in terms of cost, quality and on time delivery
  • Develop and report key performance indicators, KPIs, for supply chain operations, both internally and with external suppliers and service providers

 

Qualifications and Experience:

  • Bachelor’s degree in a Supply Chain, Logistics or related field, or a CIPS or CILT accreditation
  • A minimum of 8 years progressive experience in pharmaceutical, biotech, or biologics supply chain and logistics, with cold chain experience
  • Working knowledge and ability to apply GMPs in conformance with FDA, MHRA, EU and ICH standards for supply chain and logistics operations 
  • Experience and involvement in external regulatory inspections an advantage
  • Ability to effectively negotiate and build collaboration with 3PLs, service providers and suppliers
  • Good interpersonal, verbal and written communication skills
  • Comfortable in a fast-paced small company environment with minimal direction.

 

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Source: TCR² Therapeutics